It is widely agreed upon that the underlying ethical justification for all health-related research in humans is its scientific and social value — the prospect of generating the knowledge and means to protect and promote people’s health. However, this justification has its limits. The pursuit of scientific and social value cannot override the imperative to protect study participants, their communities, and the global population from harm. Unchecked scientific advancement carries the risk of catastrophic consequences, including potentially species-ending events. It is therefore essential to balance the drive for discovery with rigorous biosecurity measures, ensuring that research is carried out in a way that upholds human rights and protects society from its negative ramifications, both intentional and inadvertent. Current conversations surrounding biosecurity are often peripheral in nature; they consistently are reactive or opt-in rather than a proactive and mandatory part of the scientific process. OpenBio’s Biosecurity Group is dedicated to sparking necessary biosecurity conversations on Harvard’s campus and equipping students with the ethical and scientific foundations they need to lead the charge towards responsible scientific advancement. We aim to breathe new life into Harvard’s biosecurity space by fostering discussions around the intersection of biosecurity, policy, and scientific research. Our vision is to bridge different disciplines and areas of expertise on campus through speaker series, publications, and forums open to the Harvard community.